Rad/Sonic
If you don't want to use inspirations, you will want defense. Tohit debuffs are heavily resisted by AVs, and while you could survive most AVs by only using EF, your heal and kiting, doing so would most likely result in not doing enough DPS to take them down.
	Recharge will have you throwing out lots of attacks and debuffs, but you still need to stay alive and the endurance to keep fighting.  AM and some of the recovery uniques and procs should give you enough endurance to last.  Most AV killers will want to soft cap ranged defense and some kind of flight (even if it's a puchasable jet pack) to stay out of reach of the AV.
 
While Defender's radiation infection get's you most of your defense, you'll still want some of your own in case the toggle drops.
        
50s: Inv/SS PB Emp/Dark Grav/FF DM/Regen TA/A Sonic/Elec MA/Regen Fire/Kin Sonic/Rad Ice/Kin Crab Fire/Cold NW Merc/Dark Emp/Sonic Rad/Psy Emp/Ice WP/DB FA/SM
Overlord of Dream Team and Nightmare Squad
	most people which solo AVs GMs with rad/sonic go for ranged def and after this for recharge:
here a build i clicked quickly (hover is a keypower):
Hero Plan by Mids' Hero Designer 1,601
http://www.cohplanner.com/
Level 50 Technology Defender
Primary Power Set: Radiation Emission
Secondary Power Set: Sonic Attack
Power Pool: Fitness
Power Pool: Flight
Power Pool: Fighting
Power Pool: Speed
Ancillary Pool: Electricity Mastery
Hero Profile:
------------
Level 1:	Radiant Aura			Numna-Heal/EndRdx:50(A), Numna-EndRdx/Rchg:50(3), Numna-Heal/Rchg:50(7), Numna-Heal/EndRdx/Rchg:50(33), Numna-Heal:50(40), Numna-Regen/Rcvry+:50(40)
Level 1:	Shriek				Thundr-Acc/Dmg:50(A), Thundr-Dmg/EndRdx:50(5), Thundr-Dmg/Rchg:50(9), Thundr-Acc/Dmg/Rchg:50(29), Thundr-Acc/Dmg/EndRdx:50(39), Thundr-Dmg/EndRdx/Rchg:50(40)
Level 2:	Accelerate Metabolism		Efficacy-EndMod:50(A), Efficacy-EndMod/Rchg:50(3), Efficacy-EndMod/Acc/Rchg:50(7), Efficacy-Acc/Rchg:50(19), Efficacy-EndMod/Acc:50(33), Efficacy-EndMod/EndRdx:50(34)
Level 4:	Radiation Infection		DarkWD-ToHitDeb:50(A), DarkWD-ToHitdeb/Rchg/EndRdx:50(5), DarkWD-ToHitDeb/EndRdx:50(15), DarkWD-ToHitDeb/Rchg:50(15)
Level 6:	Hurdle				Jump-I:50(A)
Level 8:	Enervating Field		EndRdx-I:50(A), EndRdx-I:50(9)
Level 10:	Scream				Thundr-Acc/Dmg:50(A), Thundr-Dmg/EndRdx:50(11), Thundr-Dmg/Rchg:50(11), Thundr-Acc/Dmg/Rchg:50(17), Thundr-Acc/Dmg/EndRdx:50(27), Thundr-Dmg/EndRdx/Rchg:50(39)
Level 12:	Lingering Radiation		P'ngTtl-Acc/Slow:50(A), P'ngTtl-Dmg/Slow:50(13), P'ngTtl-Acc/EndRdx:50(13), P'ngTtl-Rng/Slow:50(27), P'ngTtl-EndRdx/Rchg/Slow:50(33), P'ngTtl--Rchg%:50(34)
Level 14:	Health				Mrcl-Rcvry+:40(A)
Level 16:	Hover				Zephyr-Travel:50(A), Zephyr-Travel/EndRdx:50(17)
Level 18:	Fly				Zephyr-Travel:50(A), Zephyr-Travel/EndRdx:50(19)
Level 20:	Stamina				P'Shift-EndMod:50(A), P'Shift-End%:50(21), P'Shift-EndMod/Rchg:50(21), P'Shift-EndMod/Acc:50(29)
Level 22:	Amplify				GSFC-ToHit:50(A), GSFC-ToHit/Rchg:50(23), GSFC-ToHit/Rchg/EndRdx:50(23), GSFC-Rchg/EndRdx:50(34), GSFC-ToHit/EndRdx:50(39), GSFC-Build%:50(42)
Level 24:	Shout				Apoc-Dmg:50(A), Apoc-Dmg/Rchg:50(25), Apoc-Acc/Dmg/Rchg:50(25), Apoc-Acc/Rchg:50(37), Apoc-Dam%:50(37)
Level 26:	Kick				Empty(A)
Level 28:	Tough				S'fstPrt-ResDam/Def+:30(A), GA-3defTpProc:50(43)
Level 30:	Weave				LkGmblr-Rchg+:50(A), LkGmblr-Def:50(31), LkGmblr-Def/EndRdx:50(31), LkGmblr-Def/EndRdx/Rchg:50(31)
Level 32:	Hasten				RechRdx-I:50(A), RechRdx-I:50(42), RechRdx-I:50(42)
Level 35:	Howl				Ragnrk-Dmg:50(A), Ragnrk-Dmg/Rchg:50(36), Ragnrk-Acc/Dmg/Rchg:50(36), Ragnrk-Acc/Rchg:50(36), Ragnrk-Dmg/EndRdx:50(37)
Level 38:	Mutation			RechRdx-I:50(A)
Level 41:	Electric Fence			Decim-Acc/Dmg:40(A), Decim-Dmg/EndRdx:40(43), Decim-Dmg/Rchg:40(43), Decim-Acc/EndRdx/Rchg:40(46), Decim-Build%:40(46)
Level 44:	Shocking Bolt			Decim-Acc/Dmg:40(A), Decim-Dmg/EndRdx:40(45), Decim-Dmg/Rchg:40(45), Decim-Acc/EndRdx/Rchg:40(45), Decim-Acc/Dmg/Rchg:40(46)
Level 47:	Thunder Strike			Stpfy-Acc/Rchg:50(A), Stpfy-EndRdx/Stun:50(48), Stpfy-Acc/EndRdx:50(48), Stpfy-Stun/Rng:50(48), Stpfy-Acc/Stun/Rchg:50(50), Stpfy-KB%:50(50)
Level 49:	Super Speed			Zephyr-Travel:50(A), Zephyr-Travel/EndRdx:50(50)
------------
Level 1:	Brawl				Empty(A)
Level 1:	Sprint				Empty(A)
Level 2:	Rest				Empty(A)
Level 1:	Vigilance	
------------
Set Bonus Totals:
9% DamageBuff(Smashing)
9% DamageBuff(Lethal)
9% DamageBuff(Fire)
9% DamageBuff(Cold)
9% DamageBuff(Energy)
9% DamageBuff(Negative)
9% DamageBuff(Toxic)
9% DamageBuff(Psionic)
7,25% Defense(Smashing)
7,25% Defense(Lethal)
7,25% Defense(Fire)
7,25% Defense(Cold)
24,4% Defense(Energy)
24,4% Defense(Negative)
6% Defense(Psionic)
8,5% Defense(Melee)
35,4% Defense(Ranged)
8,5% Defense(AoE)
4,5% Max End
2,5% Enhancement(RunSpeed)
2,5% Enhancement(JumpHeight)
2,5% Enhancement(JumpSpeed)
2,5% Enhancement(FlySpeed)
3% Enhancement(Stun)
47% Enhancement(Accuracy)
56,3% Enhancement(RechargeTime)
6% Enhancement(Heal)
18% FlySpeed
167,9 HP (16,5%) HitPoints
18% JumpHeight
18% JumpSpeed
MezResist(Held) 6,05%
MezResist(Immobilize) 5,5%
MezResist(Sleep) 2,75%
19,5% (0,33 End/sec) Recovery
48% (2,04 HP/sec) Regeneration
2,52% Resistance(Fire)
2,52% Resistance(Cold)
18% RunSpeed
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Helge corr lvl 50 rad/cold
Helge2 corr lvl 50 ice/rad
Techbothelge MM lvl 50 robo/dark
Helge Mauz def lvl 50 emp/ele
illuhelge troller lvl 50 illu/rad
Wiederbelebter helge nk lvl 50 bs/reg
Maennerschreack nightwidow lvl 44
Quantenjaeger ws lvl 3
Ranged AND AoE defense.
Helge corr lvl 50 rad/cold
Helge2 corr lvl 50 ice/rad
Techbothelge MM lvl 50 robo/dark
Helge Mauz def lvl 50 emp/ele
illuhelge troller lvl 50 illu/rad
Wiederbelebter helge nk lvl 50 bs/reg
Maennerschreack nightwidow lvl 44
Quantenjaeger ws lvl 3
A lot of melee area attacks are considered melee type anyway.
Helge corr lvl 50 rad/cold
Helge2 corr lvl 50 ice/rad
Techbothelge MM lvl 50 robo/dark
Helge Mauz def lvl 50 emp/ele
illuhelge troller lvl 50 illu/rad
Wiederbelebter helge nk lvl 50 bs/reg
Maennerschreack nightwidow lvl 44
Quantenjaeger ws lvl 3
	as far as i tried this by eochai it worked.
a thing like webnade is godlike by these things
as well most targeted aoes are subscribed with a ranged or melee component (be away of melee and let the ranged def do all the work)
        
Helge corr lvl 50 rad/cold
Helge2 corr lvl 50 ice/rad
Techbothelge MM lvl 50 robo/dark
Helge Mauz def lvl 50 emp/ele
illuhelge troller lvl 50 illu/rad
Wiederbelebter helge nk lvl 50 bs/reg
Maennerschreack nightwidow lvl 44
Quantenjaeger ws lvl 3
yeah i would slot for at least 30+ aoe def
than i interpreted the wiki wrong: http://paragonwiki.com/wiki/Defense#...Vector.29_Tags
Helge corr lvl 50 rad/cold
Helge2 corr lvl 50 ice/rad
Techbothelge MM lvl 50 robo/dark
Helge Mauz def lvl 50 emp/ele
illuhelge troller lvl 50 illu/rad
Wiederbelebter helge nk lvl 50 bs/reg
Maennerschreack nightwidow lvl 44
Quantenjaeger ws lvl 3
| than i interpreted the wiki wrong: http://paragonwiki.com/wiki/Defense#...Vector.29_Tags | 


 
        
So I have a rad/sonic at lvl 26. I really want to get him to 50 and I have a build all planned out, but its slotted for strictly recharge. I want to be able to solo AVs. Should I have slotted for something other then recharge, or will my toggles (Radiation Infection, Enervating Field) and heal be able to keep me alive?